Brief Description
One among Chaturjata group, used as Styptic drug or hemostatic agent.
अष्टाङ्गसङ्ग्रहः - सूत्रस्थानम् - १२. द्विविधौषधविज्ञानीयः
केसरं रक्तगुदजविषपित्तकफापहम्| तद्युक्तं तच्चतुर्जातं नातिशीतोष्णमुच्यते ||२६||
अभिधानमञ्जरी - मदनादिगणवर्ग - १२. अञ्जनादिवर्ग
नागाह्वं नागकुसुममुरगं स्यान्नागकेसरं कनकम् | जम्बू(न)दं च केसरमिभकुसुमं पीतकेसरं चेति |
गजपुष्पं नागपुष्पमिभकेसरमित्यपि | गजकाञ्चननागानां पर्यायैः केसरोत्तरैः |
नागकेसरमप्याहुर्भिषजो नामकोविदाः ||१९१||
कैयदेवनिघण्टु - १. ओषधिवर्ग
नागाह्वं नागकिञ्जल्कः केसरं नागकेसरम् | अहिपुष्पं हेमपुष्पं चाम्पेयं नागपुष्पकम् ||१३४५||
हिमाभं कनकं चेति दूरोहं नागरेणुकम् | नागपुष्पं कषायोष्णं तीक्ष्णं लघ्वामपाचनम् ||१३४६||
रूक्षं पित्तकफच्छर्दिखुडकण्डूविसर्पजित् | हृल्लासस्वेददौर्गन्ध्यकुष्ठतृष्णाविषापहम् ||१३४७||
धन्वन्तरिनिघण्टु - २. शतपुष्पादिवर्ग
नागपुष्पं मतं नागं केशरं नागकेशरम् | चाम्पेयं नागकिञ्जल्कं कनकं हेमकाञ्चनम् ||४९||
नागकेशरमल्पोष्णं लघु तिक्तं कफापहम् | बस्तिरुग्विषवातास्रकण्डूघ्नं शोफनाशनम् ||५०||
निघण्टुशेष - १. वृक्षकाण्ड
स्यान्नागकेसरे नागः केसरो हेमकेसरः ||१०||
दर्वीसहो दुष्प्ररोहश्चाम्पेयः स्कन्धभूषणः | नागपुष्पः कुम्भफलो हेम-सर्प-द्विपाह्वयः ||११||
निघण्टुशेषटीका व्याख्या (श्रीवल्लभगणि कृत)
नागप्रियाणि केसरवन्ति पुष्पाण्यस्य नागकेसरः, तत्र| न अगो नागः| यद् विश्वः–
नागः पन्नग-मातङ्ग-क्रूर-वारिषु तोयदे|
नागकेसर-पुन्नाग-नागदन्तक-मुस्तके|| [...] इति|
के-जले सरति केसरः, सप्तम्यलुक्; केसराः सन्त्यस्य वा, अभ्रादित्वादः प्रत्ययः “कि ज्ञाने” चिकेति केसर इति वा, मी-ज्यजि [हैमोणादिसू. ४३९] इति सरः बाहुलकान्न षत्वम्| हेमवर्णाः केसरा अस्य हेमकेसरः||१०||
दर्वीं-फणां सहति दर्वीसहः| दुष्टः प्ररोहोऽस्य दुष्प्ररोहः| चम्पादेशे भवश्चाम्पेयः| स्कन्धं भूषयति स्कन्धभूषणः| नागप्रियाणि पुष्पाण्यस्य नागपुष्पः| कुम्भाकाराणि फलान्यस्य कुम्भफलः| हेम-सर्प-द्विपेभ्यः आह्वय इति योज्यते, ततो हेम्नः-स्वर्णस्य सर्पस्य द्विपस्य च आह्वयो यस्येति हेमाह्वयः सर्पाह्वयः द्विपाह्वयः| आह च–
नागपुष्पो मतो नागः केसरो नागकेसरः|
चाम्पेयो नागकिञ्जल्कः कनकं हेम काञ्चनम्|| इति|
एतस्य लोके ‘नागकेसर’ इति प्रसिद्धिः||११||
भावप्रकाश-पूर्वखण्ड-मिश्रप्रकरण - ३. कर्पूरादिवर्ग
नागपुष्पः स्मृतो नागः केशरो नागकेशरः | चाम्पेयो नागकिञ्जल्कः कथितः काञ्चनाह्ययः ||५९||
नागपुष्पं कषायोष्णं रूक्षं लघ्वामपाचनम् | ज्वरकण्डूतृषास्वेदच्छर्दिहृल्लासनाशनम् |
दौर्गन्ध्यकुष्ठवीसर्पकफपित्तविषापहम् ||६०||
भावप्रकाश-पूर्वखण्ड-मिश्रप्रकरण - १. मिश्रवर्ग
पचेन्नामं वह्निकृद्यद्दीपनं तद्यथा मिसिः | पचत्यामं न वह्निं च कुर्याद्यत्तद्धि पाचनम् |
नागकेशरवद्विद्याच्चित्रो दीपनपाचनः ||२२१||
मदनपालनिघण्टु - ३. कर्पूरादिवर्ग
नागकेशरकं नागं चाम्पेयं केशरं गजम् | नागकेशरकं रूक्षमुष्णं लघ्वामपाचनम् |
दौर्गन्ध्यकुष्ठवीसर्पकफपित्तविषापहम् ||३०||
मदनादिनिघण्टु - १४. चतुर्दशगण
नागपुष्पमतं नागकेसरं नागकेसरम् | चाम्पेयं नागकिञ्जल्कं कनकं हेमकाञ्चनम् ||२०||
नागकेसरमत्युष्णं लघुतिक्तकफापहम् | वस्तिरुग्विषवातासृक् कण्डुघ्नं शीर्षरोपनम् ||२१||
माधवद्रव्यगुण - १. विविधौषधिवर्ग
त्वग्दोषस्वेददौर्गन्ध्यनाशनो नागकेशरः ||१३८||
राजनिघण्टु - ६. पिप्पल्यादिवर्ग
किञ्जल्कं कनकाह्वं च केशरं नागकेशरम् | चाम्पेयं नागकिञ्जल्कं नागीयं काञ्चनं तथा ||१७६||
सुवर्णं हेमकिञ्जल्कं रुक्मं हेमं च पिञ्जरम् | फणिपुन्नागयोगादि केसरं पञ्चभूह्वयम् ||१७७||
नागकेसरमल्पोष्णं लघु तिक्तं कफापहम् | बस्तिवातामयघ्नं च कण्ठशीर्षरुजापहम् ||१७८||
लघुनिघण्टु
नागपुष्पेत्विभं नागं केशरं नागकेशरम् ||१०||
चाम्पेयं नागकिञ्जल्कं कनकं हेमकाञ्चनम् | केशरं विषवीसर्परक्तहृल्लासकुष्टजित् ||११||
सोढलनिघण्टु , नामसङ्ग्रह (प्रथम भाग) - २. शतपुष्पादिवर्ग
नागपुष्पे नतं नागं केशरं नागकेशरम् | चाम्पेयं नागकिञ्जल्कं कीर्तितं हेमनामभिः ||३१६||
सिद्धभेषजमणिमाला
उष्णं रूक्षं नागपुष्पं कषायं तृष्णा छर्दि श्लेष्म वातप्रमाथि ॥
Alpha amyrin
Mesuaferrones A
Mesuaferrones B
Mesuanic acid
| Sl.No | Raw Material | Variant | Ratio | Quantity Required for 1000g | Unit |
|---|
| Rasa | कषाय - Kashaya - Astringent तिक्त - Tikta - Bitter |
|---|---|
| Guna | लघु गुणम् - Laghu Gunam - Drug property which induces lightness to body तीक्ष्णम् - Tikshnam - Drug action which irritates body by its Pungent quality उष्णं गुणम् - Ushna Gunam - Drug action which imparts heat रूक्ष गुणम् - Ruksha Gunam - Drug action which imparts dryness श्लक्ष्ण गुणम् - Shlakshna Gunam - Drug property which imparts smoothness सान्द्र गुणम् - Sandra Gunam - Drug action which imparts thickness or tightness or tight binding मृदु गुणम् - Mrudu Gunam - Drug action which imparts softness स्थिर गुणम् - Sthira Gunam - Drug action which imparts stability सूक्ष्म गुणम् - Sukshma Gunam - Drug property by virtue of which molecules of drug can eneter into minutetst spaces of body विशद गुणम् - Vishada Gunam - Drug action which cleanses the body |
| Veerya | Ushna veerya |
| Vipaka | Katu |
| Prabhava | शोणित / रक्त स्थापनम् - Shonita / Rakta Sthapanam - Styptic / Hemostatic |
| Anupanam | रोगोपशमन अनुपानम् - Anupana according to the diseases. | modal-content
| Sl.No. | Disease Factor | Name of the combination | Form of the combination | Reference | Combination products | Procedure |
|---|
| Disease Factors |
|---|
| Serial Number | Title | Result |
| 1 | Phytochemistry and Pharmacology of Mesua ferrea Linn. – A Review | Mesua ferrea is a very important plant that contains fatty acids, proteins, coumarins, flavonoids, xanthones, bis-xanthones, sterols, some phenolic and volatile oil constituents. These phytoconstitutes give very good anti-bacterial anti-fungal, anti-inflammatory, antioxidant, hepatoprotective, anti-arthritic and anti-venom and CNS activity. It can be used in diseases like rheumatism, bleeding piles, dysentery, asthama, genitor-urinary diseases, wounds and skin diseases. This plant has been reported to possess good therapeutic action against many of such diseases. The present review can give a way for a thorough evaluation and documentation of this plant. Further research on this plant can prove to be very fruitful for mankind. |
| 2 | he Effect of Ethanol Extract from Mesua ferrea Linn Flower on Alzheimer’s Disease and Its Underlying Mechanism | The effects of Mesua ferrea Linn flower (MFE) extract on the pathogenic cascade of Alzheimer’s disease (AD) were determined by an in vitro and cell culture model in the search for a potential candidate for the treatment of AD. The 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay exhibited that the MFE extract had antioxidant activities. According to the Ellman and the thioflavin T method’s result, the extracts could inhibit acetylcholinesterase and β-amyloid (Aβ) aggregation. Studies on neuroprotection in cell culture found that the MFE extract could reduce the death of human neuroblastoma cells (SH-SY5Y) caused by H2O2 and Aβ. Western blot analysis exhibited that the MFE extract alleviated H2O2-induced neuronal cell damage by downregulating the pro-apoptotic proteins, including cleaved caspase-3, Bax, and by enhancing the expression of anti-apoptotic markers including MCl1, BClxl, and survivin. Moreover, MFE extract inhibited the expression of APP, presenilin 1, and BACE, and increased the expression of neprilysin. In addition, the MFE extract could enhance scopolamine-induced memory deficit in mice. Overall, results showed that the MFE extract had several modes of action related to the AD pathogenesis cascade, including antioxidants, anti-acetylcholinesterase, anti-Aβ aggregation, and neuroprotection against oxidative stress and Aβ. Therefore, the M. ferrea L. flower might be a possibility for further development as a medication for AD. |
| 3 | Screening of anti-inflammatory activity of mesua ferrea linn Flower | In conclusion, the present study demonstrated that extracts of the flower of M. ferrea has antiinflammatory effect, without any serious toxic effect. Further detailed investigation is underway to determine the exact mechanisms, which are responsible for the anti-inflammatory activity. In conclusion, the present results provide a new way for further study in the light of developing new anti-inflammatory compounds. |
| 4 | Anti-Acne Vulgaris Potential of the Ethanolic Extract of Mesua ferrea L. Flowers | Acne vulgaris is a common chronic inflammatory skin disease. In the present study, we reported the anti-acne vulgaris effect of the Mesua ferrea (M. ferrea) flower extract. The extract was evaluated for three anti-acne-causing bacteria properties including Cutibacterium acnes (C. acnes), Staphylococcus epidermidis (S. epidermidis) and Staphylococcus aureus (S. aureus). The results indicated that the M. ferrea flower extract could be considered as the bactericidal agent against S. epidermidis and S. aureus with MIC values of 0.78 and 6.25 mg mL−1 and MBC values of 1.56 and 12.50 mg mL−1 and the bacteriostatic agent against C. acnes with MIC and MBC values of 3.12 and 25.00 mg mL−1, respectively. The extract at a concentration of 25 µg mL−1 also presented potent anti-inflammatory activity with a significant decrease of nitric oxide (NO) and tumor necrosis factor (TNF)-α productions in RAW 264.7 macrophage cells stimulated by LPS. In addition, the extract showed moderate to weak anti-oxidative capacities against DPPH, ABTS, FRAP and NO assays and also showed weak anti-tyrosinase activity. M. ferrea flower extract may serve as the alternative natural anti-acne formulations. |
| 5 | Mesua ferrae linn:- A Review of the Indian Medical Herb | M. ferrae is being used in India and various other parts of world and this plant has its special place in Ayurveda as the drug is useful for multisystem disorders and this drug proved to be most used and consumed drug by domestic industries. The plant is known for its antioxidant, analgesic, anti-inflammatory, anti-tumor, antimicrobial and several other activities and properties. It acts as ingredient for Ayurvedic as well as unani medicines. The seed oil is helpful in various skin diseases and is a useful analgesic. Nagakesara can be used over penis in case of impotently due to its stimulant action. The unripe fruits are aromatic and sudorific in nature. This plant can be used in cosmetic products. Overall M. ferrae exhibits various uses and important application which can act as gift for curing various disease and disorder. Further studies on this plant must be carried out to explore some other important, necessary and unknown benefits or Nagakesara |
| 6 | Evaluation of anticonvulsant activity of Mesua ferrea Linn. ethanolic flower extract |
Mesua ferrea was evaluated in albino mice of either sex at 3 different dose levels (200, 400 and 600 mg/kg p.o.) by MES assessed using albino mice against Maximum Electroshock Seizure (MES) test. The ethanolic extract of Mesua ferrea reduced the duration of hind limb tonic extension (HLTE) in a dose dependent manner against MES model. The ethanolic extract of Mesua ferrea inhibits MES-induced convulsions. The extract showed significant (p<0.001) against both MES (maximal electroshock) |
| 7 | https://scholar.google.co.in/scholar?start=10&q=mesua+ferrea+flower+research+paper&hl=en&as_sdt=0,5&as_vis=1 | Various research Papers |
| Type | Operator | Value | Unit | Frequency | Duration | Comment | |
|---|---|---|---|---|---|---|---|
| Adult Dosage | सूक्ष्म चूर्णम् - Sukshma Churnam - Fine Powder | <= | 3 | g | 1 times / day | 15 days | |
| Child Dosage | सूक्ष्म चूर्णम् - Sukshma Churnam - Fine Powder | <= | 1 | g | 1 times / day | 15 days |
